INFORM March 2025

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Improving the solubility of lipophilic compounds Polyethylene glycol is commonly used in drug delivery nanoparticles, but adverse reactions are becoming more common and new compounds are needed to introduce lipophilic drugs into the blood stream. Surfactant chemists are using their knowledge of micelle formation to create self-microemulsifying drug delivery systems. Read about their successful applications that resulted in getting lipophilic compounds into solution. Improving psoriasis treatment with micro-emulgels This story comes from an AOCS journal and provides another example of the research efforts currently being dedicated toward using surfactant science to expand treatment options. In this case, the authors of a Journal of Surfactants and Detergents paper described solubilizing botanicals in an ointment to relieve psoriasis symptoms. A strategy for navigating MOH risks A researcher describes the sources of potential mineral oil hydrocarbon contamination in the palm oil supply chain and how implementing a comprehensive mitigation strategy can secure a supply chain that aligns with global food safety standards.

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CONTENTS

4 Index to Advertisers 13 AOCS Events

5 Editor’s Letter 6 Division Update

28 Regulatory Review 30 Extracts & Distillates